Proteins in Medicine
Proteins can be designed in the lab, and our understanding of how they fold (and misfold) is increasing. Protein therapeutics is a rapidly growing field, and was the topic of the first Molecular Frontiers Symposium in Hungary, hosted by Eötvös Loránd University (ELTE) in Budapest. High school students from Hungary and neighboring countries participated. Aside from the lectures, there were group activities that involved making a poster about one of the speakers, and assembling a large 3D model of a protein.
Lectures, in chronological order:
Protein Dynamics Seen by NMR
Kurt Wüthrich, The Scripps Research Institute, La Jolla, CA, USA and ETH Zürich, Zürich, Switzerland
Simulating the action of Complex Biological Systems
Arieh Warshel, University of Southern California
De novo design of proteins
William F. DeGrado (Dept. of Pharmaceutical Chemistry)
Living with Oxygen
Harry B. Gray, California Institute of Technology
Protein folding is basis of life and death
Pernilla Wittung Stafshede, Chalmers University of Technology
Switches and Latches and the Control of Cell Division
Tim Hunt, Okinawa Institute of Science and Technology Graduate University
Change of protein functions with and without the gene mutations
Reiko Kuroda, Tokyo University of Science
Miracles of symbiosis
Kondorosi Éva, Hungarian Academy of Science, Szeged
Structural Basis for Activity of RyR1 Calcium Release Channels
Wayne A. Hendrickson, Columbia University, New York
The Amyloid State of Proteins and its Significance in Biology and Medicine
Christopher M. Dobson, University of Cambridge
Click below to watch the livestream recordings:
Day 1 lectures (Introduction, Wüthrich, Warshel, DeGrado, Gray, Wittung-Stafshede)
Day 2 lectures part 1 (Hunt, Kuruda, Kondorosi)
Day 2 lectures part 2 (Hendrickson, Dobson)
Time: September 14, 2017 - September 15, 2017 Location: Budapest, Hungary
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